77.A mother brings her son to the pediatrics clinic. The child rapidly
developed extensive blistering of the skin shortly after birth. He has painful
erosions of the oral mucosa and has refused ingestion. He has also had a
history of recurrent infections, with sepsis, on one occasion. Antigen map-
ping of a skin biopsy shows a split within the lamina lucida of the epider-
mal basement membrane, and junctional epidermolysis bullosa (JEB) was
the diagnosis. In which specific layer of the accompanying electron micro-
graph would you expect to see the disruption?
156 Anatomy, Histology, and Cell Biology
a. a
b. b
c. c
d. d
e. e
78.Which of the following definitively characterizes the basolateral
membrane?
a. The presence of hormone receptors
b. Endocytosis
c. Exocytosis
d. The presence of Na+,K+–ATPase
e. The presence of a glycocalyx