102.A 44-year-old African-American woman visits her family physician’s
office. She has come in for a physical examination at the urging of her hus-
band. She has no current complaints and is taking no medications. She is
allergic to erythromycin. She works as a software developer and lives with her
52-year-old husband and 12-year-old daughter. She is a nonsmoker; and
drinks an occasional glass of wine when she and her husband go out to din-
ner. She is involved in no regular exercise. Her mother is 66 and suffers from
type II diabetes, hyerlipidemia, and hypertension and had a myocardial
infarction last year. The patient’s father died of a stroke last year at the age of
- On examination, the patient’s blood pressure is 155/100, pulse 84, weight
215 lb (increased from 180 3 years ago), height 5 ft 7 in. In this patient, dur-
ing the period of weight gain which of the following responses would be most
expected in the cells shown in the photomicrograph?
Connective Tissue 179(Micrograph courtesy of Dr.WenFang Wang.)a. Up-regulation of leptin-receptors
b. Decreased synthesis of leptin
c. Decreased release of leptin into the serum
d. Increased secretion of neuropeptide Y
e. Increased release of norepinephrine from nerve terminals in adipose tissue