0071509674.pdf

(coco) #1

148.A 47-year-old man is treated with Fluoxetine hydrochloride (Prozac)
for clinical depression. This pharmaceutical agent functions through a mech-
anism that involves the structure labeled “C” in the transmission electron
micrograph below. The structure labeled “C” in the accompanying transmis-
sion electron micrograph is the site of which of the following?


Nervous System 237

(Micrograph courtesy of Drs. J. F. Hewer and T. S. Reese.)

a. Neurotransmitter reuptake in synaptic vesicles by endocytosis
b. Binding of neurotransmitter to postsynaptic receptors
c. Neurotransmitter-induced alteration of membrane permeability
d. Membrane continuity between adjacent neurons
e. Degradation of neurotransmitter

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