Microbiology and Immunology

(Axel Boer) #1
WORLD OF MICROBIOLOGY AND IMMUNOLOGY DNA (deoxyribonucleic acid)

163


Diagram depicting semiconservative DNA replication.

as that for red hair), while another sequence, such as G-C-T-
C-T-C-G...etc., might code for a different kind of protein
(such as that for blonde hair). Watson and Crick themselves
contributed to the deciphering of this genetic code, although
that process was long and difficult and involved the efforts of
dozens of researchers over the next decade.
Watson and Crick had also considered, even before
their March 7th discovery, what the role of DNA might be in

the manufacture of proteins in a cell. The sequence
that they outlined was that DNA in the nucleus of
a cell might act as a template for the formation of
a second type of nucleic acid, RNA(ribonucleic
acid). RNA would then leave the nucleus, emigrate
to the cytoplasmand then itself act as a template
for the production of protein. That theory, now
known as the Central Dogma, has since been

womi_D 5/6/03 2:09 PM Page 163

Free download pdf