Fundamentals of Medicinal Chemistry

Index

Abequose, 244

Acediasulphone, 68

Acetylcholine, 59, 60, 247, 248

Acetylcholinesterases, 189

N-Acetyl-b-D-glucosamine, 18, 242, 243

b-D-Acetylmuramic acid, 1, 242

Activation energy pathway, 208
Active site, 141, 142

Acylases, 138

Acyclovir, 156

Acylglycerols, 21

nomenclature, 21

structure, 21

Adenine, 27

Adenosine, 27

Adenosine triphosphate, 16, 28

Adenosine 3’,5’-triphosphate, 28

Adrenaline, 248

Aglycone, 15

Agonists, 144

Alanine, 2, 212,

Alcohol dehydrogenase, 186

Allylamines, 134

Aloin, 16

Amantadine, 156

Amidases, 189

Amide functional group, 4

atomic orbital structure, 5

resonance representation, 5

structural formula, 5

Amino acids, 1
classification,a,bandg,2
configurations, 4
hydrophilic nature, 3
hydrophobic nature, 3
isoelectric point, 3
nomenclature, 3

structure, 3

2-Aminoethanol, 65

Amino sugars, 10, 18

Amoxicillin, 137

Ampicillin, 137

Amsacrine, 150

Amylopectin, 19

Aminopeterin, 148

Amylose, 19

Analogue synthesis, (seeDrug synthesis)

Androgens, 204

Anomeric carbon (seeMonosaccharides)

Anomers, 12, 18

Antagonists, 145–147

Antitumour drugs, 199

Antibacterial agents, 135–138

Antibiotics (seeantibacterial agents)

Antifungal agents 132–135

O-Antigens, 244

Antiviral drugs, (seedrug action)

Antimetabolites, 147–150

Antripyrine, 169

Arachidonic acid, 20

Archidonic acid, 141

Area under the curve (AUC), 167

Arginine, 2

Arsphenamine, 39, 40

Asparagine, 2

Aspartate transcarbomylase, 143

Aspartic acid, 2, 143

Aspirin, 38, 50, 96, 140, 141, 169, 200

Atoxyl, 40

Atropine, 168

Azoles, 133–134

Bacampinicillin, 196

Bacteria, 241–244

Fundamentals of Medicinal Chemistry, Edited by Gareth Thomas
#2003 John Wiley & Sons, Ltd
ISBN 0 470 84306 3 (Hbk), ISBN 0 470 84307 1 (pbk)