Tolnftate, 133, 134
Topliss decision tree, 89–91
Topoisomerases, 150
Transfer through membranes, 62, 251–252
active transport, 251
carrier proteins, 251
classification, 251
facilated diffusion, 252
passive diffusion, 251Trials
cross over, 232
double blind, 232
Phase I, 177, 178, 181, 232, 234
Phase II, 177, 178, 181, 233
Phase III, 177, 233
Phase IV, 177, 233, 234
placebo, 232, 233
preclinical, 177, 178, 231
neonates and other specialist groups, 233Trimenlamol, 153
Trimethoprim, 150
Tristearoylglycerol, 21
Uracil, 27, 143, 149
Valine, 2, 8
Valinomycin, 135, 136
Vancomycin, 138, 168
Vidarabine, 156
Viomycin, 7
Virus, 155, 263–264
classification, 263
capsid, 263
capsomers, 263
budding, 263
provirus, 263
virons, 263
Vitamin E, 96
R and S-Warfarins, 169, 181, 182, 189
Water solubilising groups, 65
acid groups, 68
basic groups, 68
hydroxy groups, 69
method of introduction, 67, 68, 69
phosphate groups, 69
position of incorporation, 67
sulphonic acid groups, 69
type, 66Xanthine, oxidase, 186
Xenobiotics, 181, 186
Xylose, 15Zero order kinetics, 170, 176
Zidovudine, 156
Zwitterions, 3, 8, 66INDEX 285