Pharmacology for Dentistry

(Ben Green) #1
132 Section 3/ Drugs Acting on ANS

Table 3.1.1: Classification for sympathomimetics (adrenergic drugs).
I. Pressor agents
Noradrenaline (Norepinephrine) 2-4 μg/min IV infusion
Ephedrine 30-60 mg oral, 15-30 mg IM/IV
Dopamine (DOPAT) 2-50 μg/kg/min IV infusion
Phenylephrine (FRENIN) 0.5-1 mg IV, 5-10 mg IM
II. Cardiac stimulants
Adrenaline (EPINEPHRINE) 0.2-0.5 mg SC/IM
Isoprenaline (Isoproterenol; ISOPRIN) 10-20 mg SL, 1-2 mg IM
III.Bronchodilators
Adrenaline 0.2-0.5 mg SC/IM, 0.5% aerosol
Salbutamol (ASTHALIN) 2-4 mg TID-QID oral, 0.25-0.50 mg IM/SC, 100-200 mcg
(1-2 puffs) TDS-QID aerosol inhalation
Isoprenaline (ISOPRIN) 10-20 mg SL, 1-2 mg IM, 0.4-0.8 mg aerosol (AUTOHALER)
Orciprenaline (ALUPENT) 20 mg Q1D, 0.75-1.5 mg (1-2 puffs; max. of 9 mg daily)
Terbutaline (BRICANYL) 2.5-5.0 mg TDS, 250-500 μg QID SC/IM, 250-500 μg
(1-2 puffs) TDS-QID
Bambuterol (ROBUROL) 10-20 mg OD
Salmeterol (SEROBID) 25 μg BD (aerosol)
Other agents are isoetharine, fenoterol, rimeterol etc.
IV.Nasal decongestants
Ephedrine 0.5-2% topical solution, 0.75% nasal drops
Phenylephrine (ANDRE) 0.125-5% topical, 5-10% eye drops, 0.25% nasal drops
Pseudoephedrine (SUDAFED) 60 mg oral
Oxymetazoline (NASIVION) 0.025-0.05% nasal drops
Xylometazoline (OTRIVIN) 0.05-0.1% nasal drops
Naphazoline (PRIVINE) 0.1% nasal drops
V. CNS stimulants
Ephedrine 30-60 mg oral
Dexamphetamine (DEXEDRINE) 5-10 mg oral
VI.Uterine relaxants and vasodilators
Isoxsuprine (DUVADILAN) 5-10 mg oral/IM 4-6 hourly
Nylidrin (ARLIDIN) 3-12 mg oral, 5-10 mg IM
Ritodrine 0.1-0.35 mg /min IV infusion
Orciprenaline 2-8 μg/min IV infusion
Terbutaline 1-8 μg/min IV infusion
VII.Anorectics
Fenfluramine (FLABOLIN) 20-40 mg/day
Dexfenfluramine (ISOMERIDE) 15 mg BD
Sibutramine (OBESTAT) 10-15 mg OD

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