204 Section 4/ Drugs Acting on Cardiovascular & Urinary SystemTable 4.7.1: Classification of diuretics.
I. Benzothiazides and related compounds
a. Thiazides
Chlorothiazide (DIURIL) 0.5-2 g/day
Polythiazide (NEPHRIL) 1-3 mg/day
Cyclopenthiazide (NAVIDREX) 0.5-1.5 mg/day
Benzthiazide (FOVANE) 25-100 mg/day
b. Thiazide like compounds
Chlorthalidone (HYTHALTON) 50-200 mg/day
Xipamide (XIPAMID) 20-60 mg/day
Indapamide (LORVAS) 2.5 mg/day
II. High ceiling or loop diuretics
a. Sulphamoyl derivatives
Furosemide (Frusemide; LASIX) 20-80 mg/day
Bumetanide (BURINEX) 1-5 mg/day
b. Phenoxyacetic acid derivatives
Ethacrynic acid (EDECRIN) 50-150 mg/day
III.Carbonic anhydrase inhibitors
Acetazolamide (DIAMOX) 250-500 mg/day
IV.Potassium - sparing diuretics
a. Directly acting
Triamterene (DYTIDE) 50-100 mg/day
Amiloride (MIDAMOR) 5-10 mg/day
b. Aldosterone antagonist
Spironolactone (ALDACTONE) 25-200 mg/day
V. Osmotic diuretic
Mannitol (OSMITROL) 1-2 g/kg as 10 to 20% solution IV
Isosorbide (ISMOTIC) 1.5 g/kg as oral solution
Urea (sterile; UREAPHIL) 40-120 g IV in 4% or 30% solution
VI.Organic mercurials
Mersalyl sodium (SALYRGAN) 1-2 ml of 100 mg/ml solution IM twice weekly
Meralluride (MERCUHYDRIN) 1-2 ml IM twice weekly
VII.Miscellaneous or minor diuretics
a. Acidifying or alkalinizing salts
Ammonium chloride 2-4 g/day
Potassium citrate 0.3-1 g TDS
b. Xanthines
Aminophylline 250-500 mg IV