Pharmacology for Dentistry

Vaccines, Sera and Other Immunological Agents 435

BACTERIAL POLYSACCHARIDES

Typhoid, Vi-capsularBacterial Intramuscular One dose and booster at every 2 years.

polysaccharide polysaccharide

Haemophilus, Bacterial Intramuscular One dose

influenzae type b polysaccharide

conjugate (Hib) conjugated

to protein

Pneumococcal Bacterial poly- Intramuscular or One dose & booster after 6 years in patients

saccharides subcutaneous at high risk.

of 23 serotypes

Meningococcal Bacterial poly- Subcutaneous One dose

saccharides

of serotypes

A/C/Y/W-135

TOXOIDS

Tetanus-diphth- Toxoid Intramuscular Two doses at least 4 weeks apart and a third

eria (Td or DT) dose 6 to 12 months after the second and

booster at every 10 years or at age 50.

Diphtheria-tetanus- Toxoids and Intramuscular DTP at 2 months, 4 months, 6 months and at

pertussis (DTP) inactivated 12 to 18 months then at 4 to 6 years.

whole bacteria

Diphtheria-tetanus- Toxoids and Intramuscular Same as DTP vaccine.

acellular inactivated

pertussis (DTaP) bacterial

components

DTP-Haemo- Toxoids, inac- Intramuscular Same as DTP vaccine.

philus influenzae tivated whole

type b conjugate bacteria and

(DTP-Hib) bacterial poly-

saccharide

conjugated to

protein.

...Contd.

Table 13.1.2: Types of immunoglobulin.
Type of Characteristics
immunoglobulin
IgG 75 percent of the total serum immunoglobulin, small molecular wt. (1,60,000), diffuse
into the intestinal mucosa.
IgA 15 percent of the total serum immunoglobulin, found in all body secretions (internal &
external).
IgM 10 percent of total serum immunoglobulins.
IgD Normal serum contains 0.3-40 mg/100 ml of IgD.
IgE Normal serum level is 10 to 130 μg/100 ml.