84 Section 2/ Drugs Acting on CNSTable 2.4.1: Classification of non-steroidal antiinflammatory drugs.
I. Salicylates and their congeners
Acetyl salicylic acid (ASPIRIN, DISPRIN) 300-600 mg/day
Sodium salicylate 1.5-6 g/day
Salicylamide (SALAMIDE) 300-600 mg TDS-QID
Diflunisal (DOLOBID) 500 mg BD-TDS
II. Pyrazolone derivatives
Phenylbutazone (ZOLANDIN) 200-600 mg/day
Oxyphenbutazone (SIORIL) 200-600 mg/day
III. Indole derivatives
Indomethacin (INDOCAP) 25-50 mg BD-TDS
Sulindac (CLINORIL) 100-200 mg BD
IV. Propionic acid derivatives
Ibuprofen (BRUFEN) 400-800 mg TDS
Naproxen (NAPRYN) 250 mg BD
Flurbiprofen (FROBEN) 50-100 mg TDS
V. Anthranilic acid derivatives
Mefenamic acid (MEFTAL) 250-500 mg TDS
Enfenamic acid (TROMARIL) 800 mg BD-TDS
VI. Oxicam derivatives
Piroxicam (DOLONEX) 20 mg OD-BD
Tenoxicam (TOBITIL) 20 mg OD
VII. Aryl acetic acid derivatives
Diclofenac (VOVERAN) 50-150 mg BD-TDS, 25-75 mg IM
Aceclofenac (ACECLO) 100-200 mg BD
VIII.Para-aminophenol derivatives
Paracetamol (CROCIN) 0.5-1 g TDS
IX. Miscellaneous (newer compounds including selective COX-2 inhibitors)
Nimesulide (NIMULID) 100 mg BD
Ketorolac tromethamine (KETANOV) 40 mg/day (oral/IM)
Celecoxib (ZYCEL) 100-200 mg OD-BD
Nabumetone (NABUFLAM) 1-2 g/day
X. Drugs for rheumatoid arthritis
Gold compounds (Auranofin; GOLDAR) 6 mg/day OD-BD
d-Penicillamine (CILAMIN) 125-250 mg OD then 250 mg BD
Sulfasalazine (SALAZOPYRIN) 1-3 g/day
Methotrexate (FOLITRAX) 2.5-15 mg/week
XI. Drugs for gout
Colchicine (COLCHICINDON) 0.25 mg to 10 mg (max.)/day
Allopurinol (ZYLORIC) 200-800 mg/day
Probenecid (BENCID) 500 mg-1 g BD
Sulfinpyrazone (ARTIRAN) 200 mg BD (max 800 mg/day)