9780521516358book.pdf

activator, and the measurement of increase in absorbance at 340nm or by fluorescence polarisation (primary wavelength 340nm, ref ...

serum increases at the same rate as CK-MB after a myocardial infarction, has a similar time for 100% sensitivity and for peak ti ...

investigations including imaging techniques especially ultrasonography (ultrasound), magnetic resonance imaging (MRI), computeri ...

Glomerular filtration rate is the accepted best indicator of kidney function. Any pathology of the kidneys is reflected in a dec ...

Coupled enzyme assay: The method uses either creatinine kinase, pyruvate kinase or lactate dehydrogenase and measuring the chan ...

Clinical assessment of renal disease Acute renal failure (ARF) Acute renal failure is the failure of renal function over a perio ...

the body as a result of their release into the circulatory system. The result is a hormonal cascadethat incorporates an amplific ...

Thyroid function tests Approximately 1% of the population suffer from some form of thyroid disease although in many cases the sy ...

byhyperglycaemia(elevated blood glucose level) leading to long-term complications. Diabetes can be classified into a number of t ...

Non-insulin-dependent diabetes(Type 2) (also calledadult-onset diabetesandmaturity- onset diabetes), is a complex progressive m ...

Impaired glucose tolerancewhere there is an inability to metabolise glucose in the ‘normal’ way but not so impaired as to be de ...

diabetes is to maintain plasma glucose levels in the healthy range of 4–6 mM. This is typically monitored by patients themselves ...

mortality seen in diabetes. Micro-vascular disease leads to diabetic retinopathy and diabetic nephropathy and diabetic foot that ...

and is a major component of colostrum (the form of milk produced by the mammary gland immediately after giving birth). IgA is th ...

with no obvious pathology.IgE plays a major part in allergy and may be significantly raised in situations of allergic response, ...

Chace, D. H. and Kalas, T. A. (2005). A biochemical perspective on the use of tandem mass spectrometry for newborn screening and ...

17 Cell membrane receptors and cell signalling K. WILSON 17.1 Receptors for cell signalling 17.2 Quantitative aspects of recepto ...

interferons and cytokines. These molecules are either lipophilic or hydrophilic. Lipophilic signalling molecules such as the ste ...

Ligand-gated ion-channel receptors: These are responsible for the selective movement of ions such as Naþ,Kþand Clacross membra ...

Signalling co-receptors In addition to the three groups of signalling receptors discussed above, there is a group of membrane re ...