Medicinal Chemistry

(Jacob Rumans) #1

  • 5.23 Peptide Hormones and the Design of Drugs for Hypertension

    • Drug Design



  • Selected References

    • Immunomodulators and Their Receptors 6. Messenger Targets for Drug Action III:

      • 6.1 Overview of the Immune System as a Source of Drug Targets

      • 6.2 Design of Immunosuppressive Drugs

      • 6.3 Design of Immunomodulating Drugs

      • 6.4 The Clinical–Molecular Interface: Collagen Diseases





  • Selected References

    • Endogenous Cellular Structures 7. Nonmessenger Targets for Drug Action I:

      • 7.1 Cellular Structures: Relevant Anatomy and Physiology

      • 7.2 Targeting Cell Membrane Structures: Lipid Component

      • 7.3 Targeting Cell Membrane Structures: Protein Component

        • Ion Channels 7.4 Targeting Cell Membrane Proteins: Voltage-Gated



      • 7.5 Targeting Cell Membrane Proteins: Ligand-Gated Ion Channels

        • Transporter Proteins 7.6 Targeting Cell Membrane Proteins: Transmembrane



      • 7.7 Targeting Cellular Cytoplasmic Structures

      • 7.8 Targeting Cell Nucleus Structures





  • Selected References

    • Endogenous Macromolecules 8. Nonmessenger Targets for Drug Action II:

      • 8.1 Endogenous Macromolecules: Relevant Biochemistry

      • 8.2 Proteins as Drugs and Drug Design Targets: Enzymes

      • 8.3 Proteins as Drugs and Drug Design Targets: Non-Enzymes

      • 8.4 Nucleic Acids as Drugs and Drug Design Targets

      • 8.5 Lipids as Drugs and Drug Design Targets

      • 8.6 Carbohydrates as Drugs and Drug Design Targets

      • 8.7 Heterocycles as Drugs and Drug Design Targets

      • 8.8 Inorganic Substances as Drugs and Drug Design Targets





  • Selected References

    • Exogenous Pathogens and Toxins 9. Nonmessenger Targets for Drug Action III:

      • for Drug Design 9.1 Exogenous Pathogens as Targets

      • 9.2 Drug Design Targeting Prions



    • 9.3 Drug Design Targeting Viruses

    • 9.4 Drug Design Targeting Bacteria

    • 9.5 Drug Design Targeting Fungi

    • 9.6 Drug Design Targeting Parasites

    • 9.7 The Clinical–Molecular Interface: Pneumonia

    • 9.8 The Clinical–Molecular Interface: Meningitis and Encephalitis

    • 9.9 Drug Design of Therapies and Antidotes for Toxins



  • Selected References

  • Appendix: Drugs Arranged by Pharmacological Activity

  • Index

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