Medicinal Chemistry

(Jacob Rumans) #1
DESIGNING DRUG MOLECULES TO FIT RECEPTORS 169


  1. Dissolving metal reduction of an alkyne

  2. Hoffman elimination

  3. Reductive elimination of a vicinal dihalide

  4. Wittig reaction

  5. Dehydrohalogenation

  6. SN2 displacement by an acetylide anion


C≡C Bond Formation

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