Medicinal Chemistry

(Jacob Rumans) #1
DESIGNING DRUG MOLECULES TO FIT RECEPTORS 173


  1. Grignard reaction of an ester

  2. Hydration of an alkene (Markovnikov regiochemistry)

  3. Hydroboration–oxidation (anti-Markovnikov regiochemistry)

  4. Hydrolysis of an alkyl halide

  5. cis-Hydroxylation

  6. Metal hydride reduction of an aldehyde or ketone

  7. Metal hydride reduction of an ester

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