Medicinal Chemistry

(Jacob Rumans) #1

174 MEDICINAL CHEMISTRY



  1. Nucleophilic opening of an epoxide

  2. Oxymercuration–demercuration (Markovnikov regiochemistry)

  3. Cyanohydrin formation

  4. Dehydration of an amide

  5. SN2 displacement by cyanide

  6. Aminolysis of an alkyl halide


-C≡N Functional Group


-NH 2 Functional Group

Free download pdf