Medicinal Chemistry

(Jacob Rumans) #1
DESIGNING DRUG MOLECULES TO FIT RECEPTORS 179


  1. Esterification of a carboxylic acid

  2. Transesterification

  3. Treatment of an acid with thionyl chloride

  4. Amidation of a carboxylic acid derivative
    84. Beckmann rearrangement

  5. Peracid oxidation of an alkene


R-OR′Functional Group


-CONH 2 Functional Group


-COCl Functional Group

Free download pdf