18Table 1.4
Half-Lives of Selected Drugs in Patients (with Normal Renal Function)
<1 h1–4 h4–12 h12–24 h1–2 days>2 daysAdenosineAminoglycosidesAcetazolamideBromocriptineAmlodipineAmiodaroneCocaineAtropineAcyclovirChlorpromazineCarbamazepineBisphosphonatesDobutamineAzathioprineAmilorideClonidineChlorpropamideChloroquineDopamineCaptoprilCaffeineDoxycyclineClonazepamPhenobarbitalIloprostCephalosporinsChloramphenicolFluvoxamineDiazoxideThyroxineNaloxoneCimetidineClomethiazoleHaloperidolDigoxinNitroprussideCiprofloxacinClozapineMinocyclineTriiodothyroninePenicillinsColchicineDiltiazemOuabainWarfarinSuccinylcholineDiclofenacGabapentinErythromycinHydralazineEthambutolKetoconazoleFurosemideMetronidazoleIbuprofenQuinidineIsoniazidTheophyllineIsosorbideTolbutamidemononitrateTrimethoprimLevodopaValproateLidocaineVigabatrinMorphineOndansetronPravastatinProcainamideRanitidineSumatriptan(Adapted from D. G. Grahame-Smith, J. K. Aronson (2002).Clinical Pharmacology and Drug Therapy, 3rd Edn. New York: Oxford University Press. With permission.)