● Actionactivity may involve the spinal cord, brain stem, cerebellum, neurotransmitter, thereby producing a calmative effect. The limbic system, and cortical areas. gamma-aminobutyric acid (GABA), a powerful inhibitory Benzodiazepines are thought to potentiate the effects of Antianxiety Agents ●^409
2 2506_Ch25_406-416.indd Sec2:409 506 Ch 25 406 - 416 .indd suicidal patients • ChildrenAdverse Reactions and Side Effects● ● ● ● ● ● narrow-angle glaucoma • Preexisting CNS depression • Preg-● ● ● Contraindications and Precautions: Snancy and lactation • Shock • ComaUse Cautiously in:Contraindicated in:dosage recommended) • Patients with hepatic/renal/pulmonary impairment • History of drug abuse/dependence • Depressed/● Oxazepam C-IV/DName(Trade) Generic Lorazepam ePhysical and psychological dependenceRashAtaxiaHypotensionBlurred visionTo l e r a n c eDry mouthDrowsiness; dizziness, lethargyNausea and vomitingParadoxical excitationc(Ativan) 2 : 409 CategoriesControlled/ C-IV/DPregnancy • Elderly or debilitated patients (reduced (hr)Half-life 5–20 • Hypersensitivity • Psychoses • Acute 10–20 ●●Indications●Unlabeled uses:●●●Unlabeled uses:●●●● Status epilepticus Anxiety symptoms Preoperative Anxiety disorders Insomnia Acute alcohol Chemotherapy- Anxiety symptoms Management of Anxiety disordersirritable bowel induced nausea and vomitingsedationsyndromewithdrawal Caps: 10, 15, 30Inj: 2/mL, 4/mL(mg)Tabs: 0.5, 1.0, 2.0Available Forms Oral solu: 2/mL 1 10/1/10 9:39:02 AM 0 / 1 / 10 9 : 39 : 02 AM
