● Contraindicated in:● Unlabeled use:● ● Actions● ● ● Adverse Reactions and Side Effectsning therapy with buspirone. ● be withdrawn gradually from these medications before begin-block the withdrawal syndrome in these clients and they should ● zodiazepine or other sedative/hypnotic use. Buspirone will not Contraindications and Precautions: INDICATIONSand lactation • Children • Clients with a history of chronic ben-hepatic or renal impairment • Concurrent use with monoamine oxidase (MAO) inhibitorsUse Cautiously in:Generalized anxiety statesMay produce desired effects through interactions with sero-Cannot be used on a PRN basis therapy and subsiding of anxiety symptoms)Delayed onset (a lag time of 7 to 10 days between onset of tonin, dopamine, and other neurotransmitter receptorsFatigue, headacheUnknownDrowsiness, dizzinessSymptomatic management of premenstrual syndromeExcitement, nervousness • Elderly or debilitated clients • Pregnancy • Hypersensitivity to the drug • Severe
● ● Interactions● ● ● ● ● ● ● Additive effects when used with certain itraconazolePalpitations, tachycardiatrazodonediltiazem, verapamil, flIncreased risk of hepatic effects when used concomitantly with Incoordination, numbnesselevated blood pressure.phenytoin, phenobarbital, carbamazepine, flDecreased effects of buspirone with Use of buspirone with an Nausea, dry mouthIncreased effects of buspirone with dexamethasonekava, valerianIncreased serum concentrations of concomitantly with buspirone, ) nefazodone, ketoconazole, clarithromycin, uvoxamine, MAO inhibitorcimetidine, erythromycinandhaloperidolherbal products rifampin, rifabutin, ritonavir may result in uoxetine, and when used (e.g., ,
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