● ● renal, or thyroid disease • Diabetes mellitus • Urinary retention • Children younger than 12 years (● Adverse Reactions and Side Effects● ● ● ● Use Cautiously in:● ● ● ● ● ● Interactions●^448 acetazolamide, osmotic diuretics, theophylline, Fine hand tremorsWeight g a i nHypotension, arrhythmias, electrocardiogram (ECG) changes Drowsiness, dizziness, headache Polyuria, glycosurianary alkalinizers.inflSeizures HypothyroidismThe effects of lithium are decreased with concurrent use of DehydrationDry mouth, thirst LeukocytosisIncreased effects of Indigestion, nausea, anorexia The effects of lithium (and potential for toxicity) are increased with concurrent use of peridol, loop diuretics, methyldopa, nonsteroidal anti-^ ammatory drugs (NSAIDs), ●^ PSYCHOTROPIC MEDICATIONS • Elderly patients • Any degree of cardiac, neuromuscular blocking agents carbamazepine, flsafety not establishedand thiazide diuretics. uoxetine, halo-) and uri-and
2 2506_Ch27_447-471.indd 0448 506 Ch 27 447 - 471 .indAcute Mania:Route and Dosage ● ● Borderline Personality Disorder:Long-Term (Maintenance) Use:d tricyclic antidepressants Neurotoxicity may occur with concurrent use of lithium and high-potency antipsychotics Decreased pressor sensitivity of lithium.lithium0.8 to 1 mEq/L. in 3 to 4 divided doses (or 900 to 1800 mg/day [ER tabs] in 2 divided doses). Titrate dosage to maintain serum levels of 0 daily for the slow release form. Serum levels should be taken twice weekly at the initiation of therapy and until therapeutic cases during maintenance therapy every 1 to 2 months. times a day. Serum levels should be monitored in uncomplicated level has been achieved. 448 PO: 600 mg three times a day or 900 mg twice are seenor calcium channel blockers.^ PO: sympathomimetics^ PO:^ with concurrent use of 300 mg three to four 900 to 2400 mg/day with^1 10/1/10 9:39:40 AM 0 / 1 / 10 9 : 39 : 40 AM
