Sedative-HypnoticsC HAPTER^30
511
● ● ● Contraindications and Precautions: Contraindicated in:and sleep apnea • (zodiazepines • Pregnancy and lactation • Respiratory depression ActionExamplesTriazolam Generic Flurazepam Quazepam NameEstazolam(Trade) Temazepam The sedative effects involve GABA receptors in the limbic, neocortical, and mesencephalic reticular systems. inhibition Potentiate gamma-aminobutyric acid (GABA) neuronal (Halcion)(Restoril)(Doral)(Dalmane)CHEMICAL CLASS: BENZODIAZEPINESCIV/XPregnancy Controlled/CategoriesCIV/XCIV/XCIV/(Contraindicated CIV/Xin pregnancy)Tr i az ol a m) • Hypersensitivity to these or other ben-2–3 (active 41 (active 9–15(hr)Half-life 8–281.5–5.5: concurrent use with ketoconazole, metabolite, 47–100)47–100)metabolite, ●●Indications●●● (^) InsomniaInsomniaInsomniaInsomniaInsomnia Forms (mg)Available Caps: 7.5, 15, Tabs: 0.125, 0.25Tabs: 1, 2Tabs: 7.5, 15Caps: 15, 3022.5, 30