Saylor URL: http://www.saylor.org/books Saylor.org
Mechanism Symptoms DrugDangers and side
effectsPsychological
dependencePhysical
dependenceAddiction
potentialAddiction
potentialor chewedCocaineDecreased
appetite, headache Low Low ModerateAmphetaminesPossible
dependence,
accompanied by
severe “crash”
with depression as
drug effects wear
off, particularly if
smoked or injected Moderate LowModerate
to high
Depressants
Depressants change
consciousness by
increasing the
production of the
neurotransmitter GABA
and decreasing the
production of the
neurotransmitter
acetylcholine, usually at
the level of the thalamus
and the reticular
formation.
Calming effects,
sleep, pain relief,
slowed heart rate
and respirationAlcoholImpaired
judgment, loss of
coordination,
dizziness, nausea,
and eventually a
loss of
consciousness Moderate Moderate ModerateBarbiturates and
benzodiazepinesSluggishness,
slowed speech,
drowsiness, in
severe cases, coma
or death Moderate Moderate ModerateToxic inhalantsBrain damage and
death High High High
Opioids
The chemical makeup of
opioids is similar to the
endorphins, the
neurotransmitters that
serve as the body’s
“natural pain reducers.”
Slowing of many
body functions,
constipation,
respiratory and
cardiac
depression, and
the rapid
development of
toleranceOpiumSide effects
include nausea,
vomiting,
tolerance, and
addiction. Moderate Moderate ModerateMorphineRestlessness,
irritability,
headache and body
aches, tremors, High Moderate Moderate