Emergency Medicine

Critical Care Emergencies 35

Drug

Loading dose

Paediatric infusion

Dilution

Adult dose (70–80 kg)

range (< 30 kg)

Infusion pu

mp (IP)

Syringe driver

Concentration

Dose per hour

Volu

me per hour

Adrenaline

According to condition

0.05–1.0 μg/kg/min

6 mg in

3 mg in

60 μg/mL

2–20 μg/min

2–20 mL/h

(epinephrine)

1–100 μg/kg

100 mL DS

50 mL DS

Aminophylline

5.0 mg/kg in 100 mL

0.5–0.9 mg/kg/h

1000 mg in

—

2 mg/mL

0.5–0.9 mg/kg/h

17.5–30 mL/h

bStandard

DS over 20 min by IP

500 mL DS

aTransport

5.0 mg/kg in 100 mL

0.5–0.9 mg/kg/h

500 mg in

250 mg in

5 mg/mL

0.5–0.9 mg/kg/h

7–13 mL/h

DS over 20 min by IP

100 mL DS

50 mL DS

Amiodarone

2–5 mg/kg in 100 mL

5–15 μg/kg/min

600 mg in 500 mL

—

1.2 mg/mL

20–60 mg/h

17–52 mL/h

bStandard

DW over 30 min by IP

DW glass bottle.

(max. 15 mg/kg/24h)

Discard at 12 h

aTransport

2–5 mg/kg in 100 mL

5–15 μg/kg/min

300 mg in 100 mL

150 mg in

3 mg/mL

20–60 mg/h

7.5–22 mL/h

DW over 30 min by IP

DW

50 mL DW

(max. 15 mg/kg/24h)

Clonazepam

1.0–2.0 mg

5–10 μg/kg/h

10 mg in

5 mg in

0.1 mg/mL

0.35–0.7 mg/h

3.5–7.0 mL/h

100 mL DS

50 mL DS

Dobutamine

—

2–30 μg/kg/min

250 mg in

125 mg in

2.5 mg/mL

2–30 μg/kg/min

2–30 mL/h

100 mL DS

50 mL DS

Dopamine

—

Renal:

200 mg in

100 mg in

2 mg/mL

Renal:

Renal:

0.5–2.5 μg/kg/min

100 mL DS

50 mL DS

0.5–2.5 μg/kg/min

1–5 mL/h

Inotrope:

Inotrope: Inotrope:

5–20 μg/kg/min

5–20 μg/kg/min

10–40 mL/h

Fentanyl

1–5 μg/kg

1–10 μg/kg/h

1000 μg in

500 μg in

10 μg/mL

50–200 μg/h

5–20 mL/h

100 mL DS

50 mL DS

a, b See key, page 40. Abbreviations see key, page 40.