Food Chemistry

1.2 Amino Acids 27

Table 1.6.Mutagenic compounds from pyrolysates of amino acids and proteins

Mutagenic compound Short form Pyrolized Structure
compound

3-Amino-1,4-dimethyl-
5H-pyrido[4,3-b]indole

Trp-P-1 Tryptophan

3-Amino-1-methyl-
5H-pyrido[4,3-b]indole

Trp-P-2 Tryptophan

2-Amino-6-methyldipyrido
[1,2-a:3’,2’-d]imidazole

Glu-P-1 Glutamic acid

2-Aminodipyrido[1,2-a:3’,2’-d]
imidazole

Glu-P-2 Glutamic acid

3,4-Cyclopentenopyrido[3,2-a]
carbazole

Lys-P-1 Lysine

4-Amino-6-methyl-1H-2,5,10,
10 b-tetraazafluoranthene

Orn-P-1 Ornithine

2-Amino-5-phenylpyridine Phe-P-1 Phenylalanine

2-Amino-9H-pyrido[2,3-b]
indole

AαC Soya globulin

2-Amino-3-methyl-9H-
pyrido[2,3-b] indole

MeAαC Soya globulin

of tobacco smoke. They are formed by a reaction
of tryptophan and formaldehyde or acetaldehyde:

(1.57)