Pharmacology for Anaesthesia and Intensive Care

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Section IBasic principles

Salicylate:Aspirin is acetyl saliciylate and is metabolized to salicylic acid.

Thiazide:Sulphur containing heterocyclic ring, the structure of thiazide diuretics.

Xanthene:Methylxanthenes are important phosphodiesterase inhibitors, e.g.

aminophylline.

Xylidine:2,6 bismethylaminobenzene. Xylides are metabolites of many amide

anaesthetics. Lidocaine is metabolized to MEGX, monoethylglycinexylide.