Pharmacology for Anaesthesia and Intensive Care

P1: PCX

Printer: Yet To Come

9780521704632c08a

CUFX213A/Peck

9780521618168

December 28, 2007

10:40

Table 8.7.Physiochemical properties of inhaled anaesthetics.

Halothane Isoflurane Enflurane Desflurane Sevoflurane N 2 OXenon
MW 197.0 184.5 184.5 168.0 200.1 44.0 131.0
BP (◦C) 50.2 48.5 56.5 23.5 58.5 −88.0 − 108
SVP at 20◦C (kPa) 32.3 33.2 23.3 89.2 22.7^5200
MAC (%) 0.75 1.17 1.68 6.60 1.80 105 71.0
Blood:gas partition coefficient 2.40 1.40 1.80 0.42 0.70 0.47 0.14
Oil:gas partition coefficient 224 98 98 29 80 1.4 1.9
Odour non-irritant, sweet irritant non-irritant pungent non-irritant odourless odourless

125