Pharmacology for Anaesthesia and Intensive Care

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9780521704632c11a CUFX213A/Peck 9780521618168 December 28, 2007 11:59

11 Muscle relaxants and anticholinesterases

Tubocurarine

Vecuronium

Pancuronium

CH (^3) CH 3
CH 3 O CH H
3
CH 3
CH 3
CH 3
CH 3
CH 3
OH
OH
O
O
N
R
R
O
O
O C
CO
R
N
Rocuronium CH^3
CH 3
CH 3
CH 2 CHCH 2
CH 3
O
O
O
C
N
HO
N
N
N
N
Atracurium
H 3 CO
CH 3
CH 2 CH 2 CO(CH 2 ) 5 OCCH 2 CH 2
CH 2
OCH 3
OCH 3
H 3 C
H 3 CO
H 3 CO
O O N
OCH 2
OCH 2
CH 2
N
H 3 CO

• 
  
  
  
  • Figure 11.6.Structure of some non-depolarizing muscle relaxants.