Pediatric Nutrition in Practice

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of a nutrient (e.g. the provitamin A β-carotene)
already in the plant (such as in orange-f leshed
sweet potatoes) or introduce the same nutrient
where it never existed before (as in rice or cas-
sava).


Vitamins and Trace Elements Added to Foods
Extrinsic addition of micronutrients usually oc-
curs in processing or, occasionally, in the home
just prior to consumption. It includes three do-
mains: (1) enrichment (returning the nutrients
lost in processing); (2) public health-directed for-
tification (adding a nutrient or nutrients to a
widely consumed item such as salt, sugar, oil or
flour to counter a population-level deficit), and
(3) market-driven fortification (adding nutrients
to commercial products to enhance their appeal,
such as adding vitamin C to soda beverages) [4].
Fortification is a legitimate and effective pub-
lic health measure [5]. The major focus in the
publication arena had traditionally been iodine
in salt, but this has recently shifted to iron, spe-
cifically in wheat f lours and corn meals (Flour
Fortification Initiative), and other nutrients such
as retinol in cooking oils and condiments. A cre-
ative avenue for young children with nutrition-
ally precarious diets has been home fortification


in which multimicronutrient-fortified powders
(sprinkles) or spreads are combined with tradi-
tional foods to support nutrient intake. The Cen-
tral American republics have a several-decade
history of vitamin A fortification of sugar, but in-
creased sugar consumption is now leading to ex-
cessive consumption of the vitamin.

Micronutrient Supplements
The advances in pharmaceutical chemistry from
the second half of the 20th century allowed high
concentrations of vitamins and trace elements to
be formulated as capsules, tablets and syrups. In a
public health context, various forms of micronu-
trient supplementation are used – generally when
40% of the child population shows evidence of
nutrient deficiency. This is exemplified by the pe-
riodic distribution of high-dose vitamin A cap-
sules [6] and intensive courses of daily dosing of
iron and folic acid [7].
Beyond the prevention of micronutrient defi-
ciencies, some parents may be motivated to sup-
plement themselves and their children with the
motivation to decrease the risk of occurrence of
chronic diseases such as cancer, cardiovascular
diseases and cognitive decline; an analysis of the
current scientific evidence does not support such
an effect [8]. In fact, adverse outcomes from
chronic multimicronutrient supplementation
have been documented.

Factors Affecting Vitamin and Trace Element
Nutrition

Primary vitamin and trace element undernutri-
tion is the result of the oral intake of nutrients
from any combination of the aforementioned
sources not meeting the recommended amounts.
This is seen not only with poverty, famine and di-
saster but also widely in cases where the nutrient
density of the diet does not sustain nutrient re-
quirements when energy needs are fulfilled. This
is an especial concern with regard to complemen-

Ta b l e 2. Sources of micronutrients for human consump-
tion


Intrinsic micronutrients
Nutrients contained within the tissue matrix and fluid of
edible items from the animal and plant kingdoms


Extrinsic (added) micronutrients
Nutrients are added to foods as enrichment, in mass
fortification by public health mandate and/or with
discretionary fortification, as in commercial foods or
with nutrient mixes added to complementary foods
in the home


Supplemental micronutrients
Nutrients taken in pharmaceutical preparations
(chewable candies, tablets, elixirs) in individual or
combined forms


Koletzko B, et al. (eds): Pediatric Nutrition in Practice. World Rev Nutr Diet. Basel, Karger, 2015, vol 113, pp 62–67
DOI: 10.1159/000367871
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