Science - USA (2021-10-29)

excellence.rutgers.edu

Headquartered in the United States at Rutgers University,

theProteinDataBank(PDB)istheprimarydataresource

for structural biology—the world’s only free, open-access

3D digital library for proteins, DNA, and RNA: the

molecules of life found in all living organisms on the planet.

With millions of users from every country and territory

worldwide, PDB is a vital public data resource that drives

discovery and innovation in subject areas from agriculture

to zoolog y.

Rutgers Celebrates the

50 th Anniversary of the Protein Data Bank

RCSB PDB (Research Collaboratory for Structural Bioinformatics Protein Data Bank)

servesastheU.S.datacenterfortheglobalPDBarchiveandmakesPDBdata

available to all data consumers at no charge with no limitations on usage.

RCSB PDB is led by Rutgers, a preeminent national research university and New

Jersey’s top-ranked public university. Established in 1766, Rutgers is the nation’s

eighth-oldest higher education institution. Rutgers’ RCSB PDB collaborators are

University of California–San Diego/San Diego Supercomputer Center and University

of California–San Francisco.

PDB Impact and Outcomes

■180,000+3D structures of proteins, DNA, and RNA,

and growing every day

■2 million+structure data files downloaded daily by users

■1 million+published scientific research papers relied on

open access to PDB data

■90%of FDA-approved anti-cancer drugs were facilitated

by PDB structures [2010 to 2018]

■1,400+SARS-CoV-2 protein structures in PDB help

combat the pandemic

■$18 billion:That’s the replacement value of data

safeguarded by PDB at Rutgers

Structures of HIV protease (turquoise, PDB ID 3pj6) have been used to

design powerful drugs for HIV therapy. Illustrator: Maria Voigt, RCSB PDB

An Essential Global Science Resource Enabling Breakthroughs in

Biological and Biomedical Research and Education

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