Lumbar puncture may be used for head and neck tumors with examina-
tion of cerebrospinal fluid for malignant cells.
Staging
Metastasis has usually occurred by the time of diagnosis.
Five-year survival rate is near 65%, as high as 80%; tumor will not recur
if totally removed by surgery.
Children disease free for 2 years are likely cured; prognosis is poor with
relapse.
Treatment
Multimodal therapy is the treatment of choice.
Complete removal of primary tumor done when possible, however sur-
gical removal of tumors is used less frequently.
High-dose irradiation for tumors stages II through IV.
Intrathecal chemotherapy may be included in the regimen.
Chemotherapy as part of multimodal treatment with metastasis.
- Preferred chemotherapeutic agents:
Vincristine
Cisplatin
VP-16
Actinomycin D
Cyclophosphamide
Carboplatin
Topotecan
Melphalan
Doxorubicin
Ifosfamide
Etoposide
Adriamycin
Nursing Interventions
Same as with solid tumors with additions as follows:
- Assess for signs of tumor:
Inspect nasopharynx and oropharynx for visible mass. - Prepare child and family for extensive diagnostic testing.
- Support child and family during diagnosis, procedures, and treatments.
Retinoblastoma
What Went Wrong?
Retinoblastomais a rare malignant tumor of the retina of the eye accounting
for <3% of childhood cancers. It usually occurs in children <5 years of age
3
CHAPTER 8/ Oncology Conditions^169