522 Unit 4 NURSINGPRACTICE FORPSYCHIATRICDISORDERS
- Moderate:Confusion is apparent along with
progressive memory loss. The person no
longer can perform complex tasks but
remains oriented to person and place. He or
she still recognizes familiar people. Toward
the end of this stage, the person loses the
ability to live independently and requires
assistance because of disorientation to time
and loss of information such as address and
telephone number. The person may remain
in the community if adequate caregiver
support is available, but some people move
to a supervised living situation.
- Severe:Personality and emotional changes
occur. The person may be delusional, wander
at night, forget the names of his or her
spouse and children, and require assistance
in activities of daily living (ADLs). Most
people live in a nursing facility when they
reach this stage unless extraordinary
community support is available.
Etiology
Causes vary although the clinical picture is similar
for most dementias. Often no definitive diagnosis can
be made until completion of a postmortem examina-
tion. Metabolic activity is decreased in the brains of
clients with dementia (Fig. 21-1); it is not known
whether dementia causes decreased metabolic activ-
ity or if decreased metabolic activity results in de-
mentia. A genetic component has been identified for
some dementias such as Huntington’s disease. An
abnormal APOE Gene is known to be linked with
Alzheimer’s disease. Other causes of dementia are
related to infections such as HIV or Creutzfeldt-Jakob
disease.The most common types of dementia and their
known or hypothesized causes follow (APA, 2000;
Caine & Lyness, 2000; Small, 2000):
- Alzheimer’s diseaseis a progressive brain
disorder that has a gradual onset but causes
an increasing decline in functioning includ-
ing loss of speech, loss of motor function, and
profound personality and behavioral changes
Multiple cognitive deficits of dementia.
Table 21-1
COMPARISON OFDELIRIUM ANDDEMENTIA
Indicator Delirium Dementia
Onset
Duration
Level of consciousness
Memory
Speech
Thought processes
Perception
Mood
Gradual and insidious
Progressive deterioration
Not affected
Short- then long-term memory impaired, eventu-
ally destroyed
Normal in early stage, progressive aphasia in later
stage
Impaired thinking, eventual loss of thinking abilities
Often absent, but can have paranoia, hallucina-
tions, illusions
Depressed and anxious in early stage, labile mood,
restless pacing, angry out-bursts in later stages
Rapid
Brief (hours to days)
Impaired, fluctuates
Short-term memory impaired
May be slurred, rambling,
pressured, irrelevant
Temporarily disorganized
Visual or tactile hallucinations,
delusions
Anxious, fearful if hallucinating;
weeping, irritable
Adapted from American Psychiatric Association. (2000). DSM-IV-TR: Diagnostic and statistical manual of
mental disorders(4th ed.). Washington, DC: APA, & Ribby, K. J., & Cox, K. R. (1996). Development, imple-
mentation, and evaluation of a confusion protocol. Clinical Nurse Specialist, 10(5), 241–247.