Pathophysiology
- Tissue destruction results from coagulation, protein denaturation, or ionization of
cellular contents.
- skin and the mucosa of the upper airways are the sites of tissue destruction
- Disruption of the skin can lead to increased fluid loss, infection, hypothermia,
scarring, compromised immunity, and changes in function, appearance, and body
image.
- Burns that do not exceed 25% TBSA produce a primarily local response. Burns that
exceed 25% TBSA may produce both a local and a
Cardiovascular Alterations
- Hypovolemia is the immediate consequence of fluid loss and results in decreased
perfusion and oxygen delivery.
- Cardiac output decreases and BP decrease.
- SNS releases adrenaline, resulting in peripheral vasoconstriction and increase in HR.
- Patient needs immediate fluid replacement.