Clinical Manifestations
- Has a relapsing remitting (RR) course. With each relapse, recovery is usually
complete.
- Quadriparesis, cognitive dysfunction, visual loss.
- Fatigue, depression, weakness, numbness, difficulty in coordination, loss of balance,
and pain. Visual disturbances due to lesions in the optic nerves or their connections
may include blurring of vision, diplopia (double vision), patchy blindness (scotoma),
and total blindness.
Multiple Sclerosis treatment
- No cure exists for MS
- Treatment directed toward to relieving the patient's symptoms and provide continuing
support.
- Immunosuppressive agents
Myasthenia Gravis
Autoimmune disorder affecting the myoneural junction
Antibodies directed at acetylcholine at the myoneural junction impair transmission of
impulses
Manifestations
Myasthenia gravis, a motor disorder
Initially symptoms involve ocular muscles; diplopia and ptosis
Weakness of facial muscles, swallowing and voice impairment (dysphonia),
generalized weakness, weakness affects all the extremities and the intercostal
Medical Management
- Pharmacologic therapy
- Cholinesterase inhibitor: pyrostigmine bromide (Mestinon)
- Immunomodulating therapy
- Plasmapheresis
- Thymectomy