Forbidden Cures and Underground Medicine • I

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168 • HSI’s 13 Most Surprising Cures


4 Kong, W., et al. Berberine is a novel cholesterol-lowering drug working
through a unique mechanism distinct from statins. Nat Med. 10(12):1344-
1351, 2004.


  1. Hu, Y. S., et al. Berberine inhibits adipogenesis in high-fat diet-induced obesi-
    ty mice. Fitoterapia. 2009.

  2. Kelly, G. S. Bromelain: A literature review and discussion of its therapeutic
    applications. Alt Med Rev. 1(4):243-257, 1996.

  3. Amelia, M. Inhibition of mast cell histamine release by flavonoids and biofla-
    vonoids. Planta Medica. 51:16-20, 1985.

  4. Firshein, R. The Nutraceutical Revolution. Riverhead Books via Penguin Put-
    nam Inc., New York, USA. 1998:236-237.

  5. Schachter, A. N., et al. The attenuation of exercise-induced bronchospasm by
    ascorbic acid. Ann Allergy.49(3):146-151, 1982.

  6. Wolfson, D. Solving sinusitis. Nutrition Science News. April 2000.


Ancient extract conquers deadly cancers, even
some that mainstream medicine calls “incurable”



  1. Bai, X., et al. Honokiol, a small molecular weight natural product, inhibits
    angiogenesis in vitro and tumor growth in vivo. J Biol Chem. 2003.

  2. Garcia, A., et. al. Honokiol suppresses survival signals mediated by Ras-depen-
    dent phospholipase D activity in human cancer cells. Clin Cancer Res. 2008;
    14(13)

  3. Chen, F., et al. Honokiol: a potent chemotherapy candidate for human col-
    orectal carcinoma. World J Gastroenterol. 10(23):3459-3463, 2004.

  4. Hahm, E., et. al. Honokiol, a constituent of oriental medicinal herb magnolia
    officinalis, inhibits growth of PC-3 xenografts in vivo in association with apop-
    tosis induction. Clin Cancer Res. 14(4), 2008.

  5. Battle, T. E., et al. The natural product Honokiol induces caspase-dependent
    apoptosis in B-cell chronic lymphocytic leukemia (B-CLL) cells. Blood. 2005.

  6. Yang, S. E., et al. Down-modulation of Bcl-XL, release of cytochrome c and
    sequential activation of caspases during honokiol-induced apoptosis in human
    squamous lung cancer CH27 cells. Biochem Pharmacol. 63(9):1641-1651, 2002.

  7. Jiang, Q., et. al. Improved therapeutic effectiveness by combining liposomal
    honokiol with cisplatin in lung cancer model. BMC Cancer. 8:242, 2008.

  8. Hou, Y. C., et al. Honokiol and magnolol increased hippocampal acetylcholine
    release in freely-moving rats. Am J Chin Med. 28(3-4):379-384, 2000.


References

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