(^186) Medical-Surgical Nursing Demystified
PROGNOSIS
The prognosis varies depending on the underlying disease process and the ability
to reverse the coagulopathy.
HALLMARK SIGNS AND SYMPTOMS
- Unexpected bleeding—oozing from puncture sites (venipuncture, IVs, sur-
gical wounds) - Petechiae as clotting factors are lost
- Purpura as clotting factors are lost
- Severe hemorrhage as clotting factors are lost
- Uncontrolled postpartum bleeding
- Tissue hypoxia from microemboli
- Hemolytic anemia, as cells are destroyed trying to pass through partially
blocked vessels
INTERPRETING TEST RESULTS
- PT prolonged.
- PTT normal or prolonged.
- Platelet count low—thrombocytopenia.
- Fibrin degradation products elevated:
- D-dimer may be elevated.
TREATMENT
Treatment needs to decrease coagulation ability (to prevent further clot develop-
ment) and replace clotting components (to prevent further bleeding). Other inter-
ventions may be necessary depending on the locations of clot development and
any compromise of body system function due to clot formation.
- Transfusion:
- Packed RBC to replace what has been lost due to bleeding.
- Fresh frozen plasma—replaces coagulation factor deficiency.