(^202) Medical-Surgical Nursing Demystified
body destroys the platelets within the spleen. ITP is typically more common in
women and becomes chronic in adults who are in early to mid-adulthood.
PROGNOSIS
Problems for the patient are most likely the result of bleeding due to inadequate
platelets. Prednisone can control the majority of cases of ITP.
HALLMARK SIGNS AND SYMPTOMS
- Bleeding in mucous membranes or skin due to low platelet count:
- epistaxis
- oral bleeding
- menorrhagia (heavy menstrual bleeding)
- purpura
- petechiae
INTERPRETING TEST RESULTS
- Thrombocytopenia—low platelet count.
- Mild anemia—usually secondary to bleeding.
- PT normal.
- PTT normal.
TREATMENT
The use of prednisone in patients with ITP is to decrease the body’s action on the
antibody-tagged platelets. Initially, the use of prednisone will also help to enhance
vascular stability. High-dose therapy needs to be tapered down. Most patients will
be on long-term maintenance doses of prednisone. Splenectomy provides com-
plete or partial remission.
- Prednisone—bleeding will stop even before platelet count begins to rise.
- High-dose IV immunoglobulin.
- Danazol.