Different drug Regimens
6- month regimen:
Rifampicin 600mg/day
INH 300mg/day
Pyrazinamide 1gm/d
⎫
⎬
⎪ ⎪
⎪
⎭
⎪ ⎪
⎪
2month
Followed by
Rifampicin 900mg/day
INH 600mg/day
⎫
⎬
⎭
3 times/week for 4 month
4 -month Regimen:
Pyrazinamide 25 mg/kg/day (maximum 2gm)
INH 300mg/day
Rif ampicin 450 gm/day
⎫
⎬
⎪
⎭
⎪
2 month
Followed by
INH 600 mg t hrice weekly
Rif ampicin 900 gm/day
⎫
⎬
⎭
for further 2 month
Some precautions for drug usage:
- All the drugs should be administered in one dose, if they are to be
divided, they may achieve subtherapeutic levels. - It is adviced to take all drugs prior to bed times.