Different drug Regimens
6- month regimen:Rifampicin 600mg/day
INH 300mg/day
Pyrazinamide 1gm/d⎫
⎬⎪ ⎪
⎪⎭⎪ ⎪
⎪2monthFollowed by
Rifampicin 900mg/day
INH 600mg/day⎫
⎬
⎭
3 times/week for 4 month4 -month Regimen:
Pyrazinamide 25 mg/kg/day (maximum 2gm)
INH 300mg/day
Rif ampicin 450 gm/day
⎫
⎬
⎪
⎭
⎪
2 monthFollowed by
INH 600 mg t hrice weekly
Rif ampicin 900 gm/day⎫
⎬
⎭
for further 2 monthSome precautions for drug usage:
- All the drugs should be administered in one dose, if they are to be
divided, they may achieve subtherapeutic levels. - It is adviced to take all drugs prior to bed times.