Treatment of hypercalciuria: Thiazide diuretic will treat renal
hypercalciuria (hydrochlorothiazide 50 mg twice daily). If this is
proved ineffective, cellulose phosphate will treat the absorptive
hypercalciuria.
Allopurinol: which may be given in a dose of 300 mg/d plus
alkalinization of urine and restriction of dietary protein in patients
with uric acid stones.
Cystine calculi could be treated by high fluid intake, alkalinization
of urine to pH 7-7.5 and diet low in methionine and cystine.
Penicillamine 1.5 g/d may decrease urinary cystine but with high
side effects (allergic reactions affecting kidney, skin and bone
marrow).