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  1. Colour:

    • Normal: umber yellow

    • Examples of colour changes of urine:

      • Red urine: with hematuria, myoglobinuria and
        haemoglobulinuria
        (with haemoglobinuria the colour is red brown).

      • Pink: with rifampicin.

      • Orange: concentrated normal urine, urobilin, bilirubin,

      • Deep yellow: Mepacrine.

      • Milky: Chyluria.

      • Smoky: acute glomerulonephritis.





    1. Dip stick examination of urine:

      • Dip stick is a plastic strip with squares of paper impregnated with
        enzymes which change in colour on exposure to target chemicals.

      • Dip stick is used for detection of protein, ketones, glucose, pH,
        haemoglobin, bile, bacteria, pus cells and leucocytes....
        i. Proteinuria:

        • Normal protein in urine (by quantitative assessment) is <0.1
          gm/d by dip stick. It is mainly albumin and Tamm Horsfall
          protein which is synthesized by renal tubules.

        • Abnormal proteinuria may contain albumin, globulin, Bence
          Jones protein and low molecular weight protein (e.g. B-
          microglobulin).

        • Proteinuria may be of:

          • Glomerular origin e.g post infectious G.N., drug induced
            G.N., collagen disease and idiopathic G.N.

          • Tubular origin (usually low molecular weight proteins)
            e.g. heavy metals intoxication, analgesic nephropathy.



        • For more details see chapter on proteinuria (page 122 )







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