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  1. Microscopic examination of urine:

    • For cells (type and count).

    • For casts (type and count). Casts may be:

      • Fine granular casts (in chronic renal disease).

      • Hyaline casts (in chronic renal disease).

      • RBCs casts (acute nephritic syndrome).

      • WBCs casts (in U.T.I.).

      • Fat casts (in nephrotic syndrome).





  2. Crystals (Fig.2.1):



  • Crystals mainly appear in alkaline urine e.g. urate, phosphate
    (Treatment depends on the acidification of urine by vitamin C
    then follow up of pH by dip sticks).

  • Crystals in acidic urine e.g. oxalate or uric acid.



  1. Chemicals:
    Determination of 24 hours urine of some chemical substances e.g.



  • Calcium:
    Increases in hyper-parathyroidism, Vitamin D intoxication.
    Decreases in hypo-parathyroidism, rickets.

  • Porphyrin: Increases in lead poisoning, liver cirrhosis or
    infective hepatitis.

  • Urinary L.D.H. (lactic dehydrogenase): increases in carcinoma
    of the kidney, prostate and bladder, glomerular disease or
    myocardial infarction.

  • Urine catecholamine : Increase in pheochromocytoma (also
    increases level of V.M.A.) and neuroblastoma.

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