• Nail-patella syndrome ...................................................
(Hereditary onycho-Osteo-dysplasia)
This is characterized by a generalized disturbance in collagen
synthesis leading to dysplasia of nails, skeletal deformities (especially
hypoplastic displaced patella, deformed elbow, iliac horns, scoliosis) and
renal involvement.
Renal manifestations include haematuria and proteinuria, but rarely
nephrotic syndrome or renal failure occure.
Malarial Nephropathy
The disease is common in malarial endemic areas. It affects
children more than adults. It occurs in both quartan and falciparum
malaria. Quartan malarial nephropathy tends to be chronic and progressive
while falciparum malarial nephropathy tends to resolve completely after
antimalarial treatment.
Schistosomal Nephropathy
Incidence:
In Egypt, proteinuria was detected in 20 percent of asymptomatic
patients with active schistosoma mansoni infection. In the same centre,
schistosomal specific kidney lesions were documented in 65 per cent of
patients with active schistosoma mansoni who present with overt nephrotic
syndrome.
the disease is more common in patients with advanced hepatosplenic
disease in comparison with early intestinal disease.
Clinical and histopathologic manifestations of schistosomal
glomerulopathy:
