CHAPTER 1 Cardiovascular System^43
onset of pericarditis. Pericarditis may be caused by any infectious agent, AMI,
malignancy, autoimmune diseases, or drug reaction.
PROGNOSIS
Outcome of acute pericarditis is often self-limited, resolving in two to six weeks.
Patients are typically treated with nonsteroidal anti-inflammatories (NSAIDs) to
decrease the inflammation of the pericardium.
HALLMARK SIGNS AND SYMPTOMS
- Acute:
- A grating heart sound heard (pericardial friction rub) due to friction from
inflammation between the layers surrounding the heart - Sudden sharp pain over the precordium (mid- to lower sternum area) radi-
ating to the neck, shoulders, back, and arm - Pain decreases when the patient leans forward, sits up
- Teeth pain, anxiety, myalgias
- Difficulty breathing (dyspnea), rapid breathing (tachypnea)
- Arrhythmias
- A grating heart sound heard (pericardial friction rub) due to friction from
- Chronic:
- Enlarged liver (hepatomegaly), ascites because of liver congestion
- Increased fluid retention due to ineffective pumping
- Pericardial friction rub
INTERPRETING TEST RESULTS
- Increase WBC and sed rate (the rate at which red blood cells settle in a test
tube. A high rate indicates inflammation), thyroid studies, renal function, Rh
factor, ANA complement. - May see increased CK (creatine kinase), LDH (lactate dehydrogenase), liver
enzymes levels. - EKG.
- Sinus tachycardia.