TURNING OFF CANCER
CHART 3.3: DECREASE IN CARCINOGEN BINDING TO NUCLEUS
COMPONENTS CAUSED BY LOW-PROTEIN FEEDING
72 % Decrease
in DNA Binding
DNA
68% Decrease
in Chromatin 1--------1
Binding
Chromatin
66% Decrease
in Protein
Binding
Protein
53
ery time we searched for a way, or mechanism, by which protein works
to produce its effects, we found one! For example, we came to discover
that low-protein diets, or their equivalents, reduce tumors by the fol-
lowing mechanisms:
- less aflatoxin entered the celF4-26
- cells multiplied more slowlyl8
- multiple changes occurred within the enzyme complex to reduce
its activity2 7 - the quantity of critical components of the relevant enzymes was
reduced^28 , 29 - less aflatoxin-DNA adducts were formed^23 , 30
The fact that we found more than one way (mechanism) that low-
protein diets work was eye-opening, It added a great deal of weight to
the results of the Indian researchers, It also suggested that biological
effects, although often described as operating through single reactions,
more likely operate through a large number of varied simultaneous re-
actions, very likely acting in a highly integrated and concerted manner,
Could this mean that the body had lots of backup systems in case one
was bypassed in some way? As research unfolded in the subsequent
years, the truth of this thesis became increasingly evident.
From our extensive research, one idea seemed to be clear: lower pro-
tein intake dramatically decreased tumor initiation, This finding, even
though well substantiated, would be enormously provocative for many
people.