BIOINORGANIC CHEMISTRY A Short Course Second Edition

(lu) #1

NUCLEAR MAGNETIC RESONANCE 121


Figure 3.18 Secondary structure of matrix metalloproteinase 12 (MMP12): (A) PDB:
1YCM (structure determined using solution NMR) and (B) PDB: 1RMZ (structure
determined using X - ray crystallography). Visualized using The PyMOL Molecular
Graphics System and ChemDraw Ultra, version 10.0. (Printed with permission of
Delano Scientifi c, LLC and CambridgeSoft Corporation.) (See color plate)


gly188

ser189

gly190

asn153, thr154

asp171

met125, asn126, arg127

ser207

residues 242-248

leu147

PDB: 1RMZ

B


gly155

gly190

A

asp171
thr122, pro123

ser207

asn246

leu147

gly227

PDB: 1YCM

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