sequence, the availability of materials, and other factors.
3) In reality, it may be necessary to try several approaches in the laboratory in order
to find the most efficient or successful route.4.20B IDENTIFYING PRECURSORS
Retrosynthetic Analysis
CCCH 2 CH 3 CC − CCHSynthesis
CCH(NaNH−NH^2
3 ) CC^−Na+ BrCH^2 CH^3
(−NaBr)
CCCH 2 CH 3Retrosynthetic Analysis
CH 3 CH 2 CH 2 CH 2 CHCH 3CH 32-MethylhexaneCH 3 C CCH 2 CHCH 3CH 3+
+ H
CH 3 CC −CH 3 X + C CCH 2 CHCH 3CH 3
−+ XCH 2 CHCH 3CH 3( 1 o, but branched at second carbon)HC CCH 2 CH 2 CHCH 3CH 3
HC C −XCH 2 CH 2 CHCH 3+ CH 3CH 3 CH 2 C CCHCH 3CH 3
+ XCHCH 3CH 3(a 2o alkyl halide)
XCH 2 CH 3 C CCHCH 3CH 3
+ −3 CH 2 CC C−