Advices For Studying Organic Chemistry

(Wang) #1
(R)-Lactic acid

CH 3 (S)-Lactic acid

OH

H

HOOC

Same as

Same as

90 o rotation

COOH
HOH
CH 3

C

COOH
H OH
CH 3

C

OH
HOOC CH 3
H


  1. One group hold steady and the other three can rotate:


Hold steady
COOH
HOH
CH 3

COOH
HO CH 3
H

Same as


  1. Differentiate different Fischer projections:


OH

H 3 C CH 2 CH 3

H

CH 3

HO H

CH 2 CH 3

CH 2 CH 3

H CH 3

OH

ABC

CH 3

HO H


CH 2 CH 3

B

H
CH 3

OH
CH 2 CH 3
OH

H 3 C CH 2 CH 3

H

A

Hold CH 3 Hold CH 2 CH 3
Rotate other
three groups
clockwise

Rotate other
three groups
clockwise
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