Mind, Brain, Body, and Behavior

94 FARRERAS

Roger K. McDonald, M.D.

Courtesy of the National Institute

of Mental Health

When a second ward at the Clinical Center opened up for the

laboratory in July 1957, the laboratory began a series of long-range, multi­

disciplinary studies on the biological aspects of schizophrenia.^24 From

this point on, the clinical and basic sections did not work so much as

distinct sections as they did collaboratively on the following areas:

1) the metabolism of epinephrine and norepinephrine; 2) the metabo­

lism related to the nervous system or behavior, specifically, the action

of thyroxine on protein synthesis, the metabolism of histidine and other

amino acids, and the enzymatic activities in blood; 3) a multidisciplinary

study of possible biological factors involved in the etiology and pathogene­

sis of schizophrenia;^25 4) the relationship between brain stem reticular

Louis Sokoloff, M.D.

Courtesy of the National Library

of Medicine