1298 10 DECEMBER 2021 • VOL 374 ISSUE 6573 science.org SCIENCE
PHOTO: JACQUELYN SMALE
CONTENTS
1310 X-ray telescope to study how
magnetic objects sculpt light
NASA mission could reveal engines driving
black hole jets By D. Clery
1311 Key cancer results failed
to be reproduced
Project to replicate high-impact
preclinical cancer studies delivers
sobering verdict
By J. Kaiser
FEATURES
1312 World wide web
Researchers are weaving optical fibers
into a low-cost network of seismic sensors
that can probe Earth’s hidden dynamics
B y P. Vo o s e n
PODCAST
1312
NEWS
IN BRIEF
1302 News at a glance
IN DEPTH
1304 How bad is Omicron?
Some clues are emerging
New variant appears to evade immunity
and shows signs of spreading more rapidly
By K. Kupferschmidt and G. Vogel
1305 Archaeologist reinstated
as Max Planck director
After allegations of bullying, Nicole Boivin
returns to supervisory role By A. Curry
1306 Trial of Harvard chemist poses
test for U.S.’s China Initiative
Prosecution of Charles Lieber “misguided,”
critics say By J. Mervis
1307 Gene editing produces
single-sex litters in mice
CRISPR approach may curb culling of lab
animals, chicks By E. Pennisi
1308 How pandemic pressure is
re-engineering clinical trials
COVID-19 spurred nimbler trials that
demand less of patients—and many changes
may stick By J. Couzin-Frankel
1319 Interactomes in the era
of deep learning
Deep learning provides an atomic
snapshot of the yeast protein
interactome By J. Pereira and T. Schwede
RESEARCH ARTICLE p. 1340
1321 Keep it simple and switch
to pure tellurium
Tellurium switch operates memories
through crystalline-liquid-crystalline
phase changes
By R. Calarco and F. Arciprete
REPORT p. 1390
1322 Artificial intelligence “sees”
split electrons
Machine-learning creates a density
functional that accounts for fractional
charge and spin By J. P. Perdew
REPORT p. 1385
1323 Martian water escape
and internal waves
Lower atmospheric processes are vital
for assessing water loss from Mars
By E. Yiğit
1325 Oncolytic virotherapy
as immunotherapy
Recognizing immune responses to
oncolytic virotherapy opens the way for
new combinations By A. Melcher et al.
10 DECEMBER 2021
VOLUME 374 • ISSUE 6573
Researchers unspool fiber optic cables used to eavesdrop on the rumblings beneath Mount Meager, a volcano in British Columbia, Canada.
INSIGHTS
PERSPECTIVES
1318 A lipid primes the final cut
in dividing cells
A newly described pathway activates
separation of lens cells at the end of
cytokinesis By J. A. Brill and A. Wilde
RESEARCH ARTICLE p. 1339