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(Brent) #1
Japanese kampo medicine | 243

Kakkonto
Suppression of fever
Anti-allergic action
Suppression of pneumonia due to influenza virus infection
Reduction of increased IL-1alevel due to influenza virus infection


Hachimijiogan
Suppression of experimental diabetes
Suppression of the circulatory disorder
Inhibition of aldose reductase activity
Improvement of bone metabolism
Increment of testosterone level in testicle tissue
Diuretic action
Suppression of hypertension
Improvement of renal failure


Shosaikoto
Suppression of experimental hepatic injury
Suppression of decrease of bloodstream in liver
Enhancement of liver regeneration
Suppression of liver fibrosis
Immunomodulating activity
Clearance activity of immune complex
Antiallergic action
Anti-inflammatory action
Suppression of production of active oxygen molecules


Orengedokuto
Increment of blood circulation level in hippocampus of brain
Suppression of increased hypertension in SHR-SP
Decrease of total cholesterol, triglyceride and phospholipids level in heart
Suppression of platelet aggregation
Suppression of gastric mucous membrane injury
Anti-inflammatory activity
Suppression of lipid peroxidation
Improvement of experimental colitis


Shoseiryuto
Antiallergic activity
Anti-inflammatory activity
Suppression of chemical mediators (histamine, leukotriene, PAF) production on release
Increment of arachidonic acid metabolism (PGE 2 production)
Anti-influenza virus activity in allergic pulmonary inflammation model mice


Tokishakuyakusan
Action on hormones
Increment of progesterone production from ovarian cells by stimulation with hCG
Enhancement of LH and FSH secretions from rat ptosis cultured cells
Enhancement of estradiol secretion
Increments of uterus weight and number of oestrogen receptor in uterus
Induction of ovulation
Suppression of contraction of uterus
Action to blood coagulation


Table 8.5Pharmacological activities of kampo medicines


Continued
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