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17 DECEMBER 2021

SPECIAL ISSUE

science.org

All-season thermal

regulation pp. 1501 & 1504

Grouping cancer-associated

T cells pp. 1446 & 1462

Drought eff ects in Biosphere 2

pp. 1442 & 1514

2021

BREAKTHROUGH OF THE YEAR

l

pp.

sphere 2 2 ing c ated